Mitosis as drug target

The nuclear division cycles of the malaria parasite are of particular interest, since they differ from traditional mitosis in several aspects and are therefore a promising source for novel antimalarial drug target. To elucidate the function of selected cell division associated proteins their localization and movement during the nuclei division is be tracked in fluorescence-tagged parasites or labeled with specific antibodies (on the left) and monitored within the Nikon Eclipse T_i – Life Cell Imaging System (on the right).