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  2. Technische Fakultät
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  1. Startseite
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Publications

Bereichsnavigation: Research
  • Research Groups
    • Muscle Opto-Biomechatronics
      • The MyoRobot
      • The MechaMorph
      • The IsoStretcher
      • Virtual Laboratory
    • Malaria Biotechnology
      • RG Protein Engineering
      • Metabolic enzymes as drug targets
      • Identification of novel antimalarial compounds
      • Mitosis as drug target
      • Identification of transporters of the MGC-basic proteins
      • Characterization of drug-resistance transporters of the digestive vacuole
      • Malaria vaccine directed against blood stages
    • Tissue Engineering
      • Bone Tissue Engineering
      • Research Topic 2 (TE)
      • Research Topic 3 (TE)
    • Optical Technologies in Life Sciences
      • Label-free Multiphoton Imaging
      • Multiphoton Endomicroscopy for Life Science and Medicine
      • Raman Spectroscopy of Biological Tissue
      • PiezoGRIN: Multiphoton Imaging under high Pressures
    • High-throughput Biology & Robophotonics
      • High-throughput Biology & Functional Neurogenomics
      • Robophotonics & Rapid Prototyping
  • Collaborations
  • Publications

Publications

2022

  • Gineste C., Youhanna S., Vorrink SU., Henriksson S., Hernández A., Cheng AJ., Chaillou T., Buttgereit A., Schneidereit D., Friedrich O., Hultenby K., Bruton JD., Ivarsson N., Sandblad L., Lauschke VM., Westerblad H.:
    Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control
    In: iScience 25 (2022), Art.Nr.: 105654
    ISSN: 2589-0042
    DOI: 10.1016/j.isci.2022.105654
  • Haug M., Reischl B., Nübler S., Kiriaev L., Mázala DA., Houweling PJ., North KN., Friedrich O., Head SI.:
    Absence of the Z-disc protein α-actinin-3 impairs the mechanical stability of Actn3KO mouse fast-twitch muscle fibres without altering their contractile properties or twitch kinetics
    In: Skeletal Muscle 12 (2022), Art.Nr.: 14
    ISSN: 2044-5040
    DOI: 10.1186/s13395-022-00295-8
  • Haug M., Ritter P., Michael M., Reischl B., Schürmann S., Prölß G., Friedrich O.:
    Structure-Function Relationships in Muscle Fibres: MyoRobot Online Assessment of Muscle Fibre Elasticity and Sarcomere Length Distributions
    In: IEEE Transactions on Biomedical Engineering 69 (2022), S. 148-155
    ISSN: 0018-9294
    DOI: 10.1109/TBME.2021.3089739
  • Heiß R., Tan L., Schmidt S., Regensburger A., Ewert F., Mammadova D., Bühler A., Vogel-Claussen J., Voskrebenzev A., Rauh M., Rompel O., Nagel AM., Levy S., Bickelhaupt S., May M., Uder M., Metzler M., Trollmann R., Wölfle J., Wagner A., Knieling F.:
    Pulmonary Dysfunction after Pediatric COVID-19
    In: Radiology (2022)
    ISSN: 0033-8419
    DOI: 10.1148/radiol.221250
  • Kara A., Distler T., Polley C., Schneidereit D., Seitz H., Friedrich O., Tihminlioglu F., Boccaccini AR.:
    3D printed gelatin/decellularized bone composite scaffolds for bone tissue engineering: Fabrication, characterization and cytocompatibility study
    In: Materials Today Bio 15 (2022)
    ISSN: 2590-0064
    DOI: 10.1016/j.mtbio.2022.100309
  • Kratzer S., Arkudas A., Himmler M., Schubert DW., Schneidereit D., Bauer J., Friedrich O., Horch RE., Cai A.:
    Vascularization of Poly-ε-Caprolactone-Collagen I-Nanofibers with or without Sacrificial Fibers in the Neurotized Arteriovenous Loop Model
    In: Cells 11 (2022), S. 3774
    ISSN: 2073-4409
    DOI: 10.3390/cells11233774
  • Kreiß L., Ganzleben I., Mühlberg A., Ritter P., Schneidereit D., Becker C., Neurath M., Friedrich O., Schürmann S., Waldner M.:
    Label-free analysis of inflammatory tissue remodeling in murine lung tissue based on multiphoton microscopy, Raman spectroscopy and machine learning
    In: Journal of Biophotonics (2022)
    ISSN: 1864-063X
    DOI: 10.1002/jbio.202200073
  • Kreiß L., Thoma OM., Lemire S., Lechner K., Carlé BE., Dilipkumar A., Kunert T., Scheibe K., Heichler C., Merten AL., Weigmann B., Neufert C., Hildner K., Vieth M., Neurath M., Friedrich O., Schürmann S., Waldner M.:
    Label-Free Characterization and Quantification of Mucosal Inflammation in Common Murine Colitis Models With Multiphoton Imaging
    In: Inflammatory Bowel Diseases (2022)
    ISSN: 1078-0998
    DOI: 10.1093/ibd/izac114
  • Kunze P., Kreiß L., Novosadová V., Roehe AV., Steinmann S., Prochazka J., Geppert C., Hartmann A., Schürmann S., Friedrich O., Schneider-Stock R.:
    Multiphoton Microscopy Reveals DAPK1‐Dependent Extracellular Matrix Remodeling in a Chorioallantoic Membrane (CAM) Model
    In: Cancers 14 (2022), Art.Nr.: 2364
    ISSN: 2072-6694
    DOI: 10.3390/cancers14102364
  • Lemire S., Thoma OM., Kreiß L., Völkl S., Friedrich O., Neurath M., Schürmann S., Waldner M.:
    Natural NADH and FAD Autofluorescence as Label-Free Biomarkers for Discriminating Subtypes and Functional States of Immune Cells
    In: International Journal of Molecular Sciences 23 (2022), Art.Nr.: 2338
    ISSN: 1422-0067
    DOI: 10.3390/ijms23042338
  • Michael M., Kovbasyuk L., Ritter P., Reid MB., Friedrich O., Haug M.:
    Redox Balance Differentially Affects Biomechanics in Permeabilized Single Muscle Fibres—Active and Passive Force Assessments with the Myorobot
    In: Cells 11 (2022), Art.Nr.: 3715
    ISSN: 2073-4409
    DOI: 10.3390/cells11233715
  • Müller-Seubert W., Ostermaier P., Horch RE., Distel L., Frey B., Cai A., Arkudas A.:
    Intra-and Early Postoperative Evaluation of Malperfused Areas in an Irradiated Random Pattern Skin Flap Model Using Indocyanine Green Angiography and Near-Infrared Reflectance-Based Imaging and Infrared Thermography
    In: Journal of Personalized Medicine 12 (2022), Art.Nr.: 237
    ISSN: 2075-4426
    DOI: 10.3390/jpm12020237
  • Ritter P., Cai A., Reischl B., Fiedler M., Prölß G., Frie B., Kretzschmar E., Michael M., Hartmann K., Lesko C., Salti H., Arkudas A., Horch RE., Paulsen F., Friedrich O., Haug M.:
    MyoBio: An automated bioreactor system technology for standardized perfusion-decellularization of whole skeletal muscle
    In: IEEE transactions on bio-medical engineering (2022)
    ISSN: 1558-2531
    DOI: 10.1109/TBME.2022.3142317
  • Ritter P., Nübler S., Buttgereit A., Smith LR., Mühlberg A., Bauer J., Michael M., Kreiß L., Haug M., Barton E., Friedrich O.:
    Myofibrillar Lattice Remodeling Is a Structural Cytoskeletal Predictor of Diaphragm Muscle Weakness in a Fibrotic mdx (mdx Cmah(-/-)) Model
    In: International Journal of Molecular Sciences 23 (2022)
    ISSN: 1422-0067
    DOI: 10.3390/ijms231810841
  • Ryma M., Genc H., Nadernezhad A., Paulus I., Schneidereit D., Friedrich O., Andelovic K., Lyer S., Alexiou C., Cicha I., Groll J.:
    A Print-and-Fuse Strategy for Sacrificial Filaments Enables Biomimetically Structured Perfusable Microvascular Networks with Functional Endothelium Inside 3D Hydrogels
    In: Advanced Materials (2022)
    ISSN: 0935-9648
    DOI: 10.1002/adma.202200653
  • Schmalzl A., Leupold T., Kreiß L., Waldner M., Schürmann S., Neurath M., Becker C., Wirtz S.:
    Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection
    In: Nature Communications 13 (2022), Art.Nr.: 5730
    ISSN: 2041-1723
    DOI: 10.1038/s41467-022-33326-5
  • Schmid R., Schmidt S., Detsch R., Horder H., Blunk T., Schrüfer S., Schubert DW., Fischer L., Thievessen I., Heltmann-Meyer S., Steiner D., Schneidereit D., Friedrich O., Grüneboom A., Amouei H., Wajant H., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
    A new printable alginate / hyaluronic acid / gelatin hydrogel suitable for biofabrication of in vitro and in vivo metastatic melanoma models
    In: Advanced Functional Materials Volume 32 (2022)
    ISSN: 1616-301X
    DOI: 10.1002/adfm.202107993
  • Simon N., Voigtländer C., Kappes B., Rohrbach P., Friedrich O.:
    PfMDR1 Transport Rates Assessed in Intact Isolated Plasmodium falciparum Digestive Vacuoles Reflect Functional Drug Resistance Relationship with pfmdr1 Mutations
    In: Pharmaceuticals 15 (2022), Art.Nr.: 202
    ISSN: 1424-8247
    DOI: 10.3390/ph15020202
  • Xu S., Yang X., Liu W., Jonsson J., Qian R., Konda PC., Zhou KC., Kreiß L., Wang H., Dai Q., Berrocal E., Horstmeyer R.:
    Imaging Dynamics Beneath Turbid Media via Parallelized Single-Photon Detection
    In: Advanced Science (2022)
    ISSN: 2198-3844
    DOI: 10.1002/advs.202201885

2021

  • Bojarski C., Waldner M., Rath T., Schürmann S., Neurath M., Atreya R., Siegmund B.:
    Innovative Diagnostic Endoscopy in Inflammatory Bowel Diseases: From High-Definition to Molecular Endoscopy
    In: Frontiers in Medicine 8 (2021), Art.Nr.: 655404
    ISSN: 2296-858X
    DOI: 10.3389/fmed.2021.655404
  • Dakhil H., Basu SK., Steiner S., Gerlach Y., Soller A., Pan S., Germann N., Leidenberger M., Kappes B., Wierschem A.:
    Buffered λ-DNA solutions at high shear rates
    In: Journal of Rheology 65 (2021), S. 159-169
    ISSN: 0148-6055
    DOI: 10.1122/8.0000136
  • Distler T., Kretzschmar L., Schneidereit D., Girardo S., Goswami R., Friedrich O., Detsch R., Guck J., Boccaccini AR., Budday S.:
    Mechanical properties of cell- and microgel bead-laden oxidized alginate-gelatin hydrogels
    In: Biomaterials Science (2021), Art.Nr.: d0bm02117b
    ISSN: 2047-4830
    DOI: 10.1039/D0BM02117B
    URL: https://pubs.rsc.org/en/content/articlelanding/2021/bm/d0bm02117b
  • Distler T., Polley C., Shi F., Schneidereit D., Ashton MD., Friedrich O., Kolb JF., Hardy JG., Detsch R., Seitz H., Boccaccini AR.:
    Electrically Conductive and 3D-Printable Oxidized Alginate-Gelatin Polypyrrole:PSS Hydrogels for Tissue Engineering
    In: Advanced Healthcare Materials (2021)
    ISSN: 2192-2640
    DOI: 10.1002/adhm.202001876
  • Eggert S., Kahl M., Bock N., Meinert C., Friedrich O., Hutmacher DW.:
    An open-source technology platform to increase reproducibility and enable high-throughput production of tailorable gelatin methacryloyl (GelMA) - based hydrogels
    In: Materials and Design 204 (2021), Art.Nr.: 109619
    ISSN: 0261-3069
    DOI: 10.1016/j.matdes.2021.109619
  • Gilbert D., Friedrich O., Lesko C., Hartmann K.:
    Hilfsmittel und Verfahren für zellbasiertes high content imaging
    In: BioSpektrum 27 (2021), S. 156-159
    ISSN: 0947-0867
    DOI: 10.1007/s12268-021-1542-3
  • Goossens C., Weckx R., Derde S., Van Helleputte L., Schneidereit D., Haug M., Reischl B., Friedrich O., Van Den Bosch L., Van Den Berghe G., Langouche L.:
    Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model
    In: Journal of Cachexia, Sarcopenia and Muscle (2021)
    ISSN: 2190-5991
    DOI: 10.1002/jcsm.12668
  • Guo Y., Merten AL., Schöler U., Yu ZY., Cvetkovska J., Fatkin D., Feneley MP., Martinac B., Friedrich O.:
    In vitro cell stretching technology (IsoStretcher) as an approach to unravel Piezo1-mediated cardiac mechanotransduction
    In: Progress in Biophysics & Molecular Biology 159 (2021), S. 22-33
    ISSN: 0079-6107
    DOI: 10.1016/j.pbiomolbio.2020.07.003
  • Heilmann M., Breiter R., Becker A.:
    Towards rare earth element recovery from wastewaters: biosorption using phototrophic organisms
    In: Applied Microbiology and Biotechnology (2021)
    ISSN: 0175-7598
    DOI: 10.1007/s00253-021-11386-9
  • Heltmann-Meyer S., Steiner D., Mueller C., Schneidereit D., Friedrich O., Salehi S., Engel F., Arkudas A., Horch RE.:
    Gelatin methacryloyl is a slow degrading material allowing vascularization and long-term use in vivo
    In: Biomedical Materials 16 (2021)
    ISSN: 1748-6041
    DOI: 10.1088/1748-605X/ac1e9d
  • Kah DT., Winterl A., Přechová M., Schöler U., Schneider W., Friedrich O., Gregor M., Fabry B.:
    A low-cost uniaxial cell stretcher for six parallel wells
    In: HardwareX 9 (2021), Art.Nr.: e00162
    ISSN: 2468-0672
    DOI: 10.1016/j.ohx.2020.e00162
  • Kahl M., Schneidereit D., Bock N., Friedrich O., Hutmacher DW., Meinert C.:
    MechAnalyze: An Algorithm for Standardization and Automation of Compression Test Analysis
    In: Tissue Engineering - Part C: Methods 27 (2021), S. 529-542
    ISSN: 1937-3392
    DOI: 10.1089/ten.tec.2021.0170
  • Martonová D., Alkassar M., Seufert J., Holz D., Duong MT., Reischl B., Friedrich O., Leyendecker S.:
    Passive mechanical properties in healthy and infarcted rat left ventricle characterised via a mixture model
    In: Journal of the Mechanical Behavior of Biomedical Materials 119 (2021), Art.Nr.: 104430
    ISSN: 1751-6161
    DOI: 10.1016/j.jmbbm.2021.104430
  • Minkov L., Dück J., Hassan MMA., Ali MAM., Farghaly MG.:
    Optimizing the separation characteristics of the waterinjection hydrocyclone using mathematical modelling
    In: Mining of Mineral Deposits 15 (2021), S. 114-121
    ISSN: 2415-3435
    DOI: 10.33271/mining15.04.114
  • Schmid R., Schmidt S., Detsch R., Horder H., Blunk T., Schrüfer S., Schubert DW., Fischer L., Thievessen I., Heltmann-Meyer S., Steiner D., Schneidereit D., Friedrich O., Grüneboom A., Amouei H., Wajant H., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
    A new printable alginate / hyaluronic acid / gelatin hydrogel suitable for biofabrication of in vitro and in vivo metastatic melanoma models
    In: Advanced Functional Materials (2021)
    ISSN: 1616-301X
    DOI: 10.1002/adfm.202107993
    URL: https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202107993
  • Schmid R., Schmidt S., Detsch R., Horder H., Blunk T., Schrüfer S., Schubert DW., Fischer L., Thievessen I., Heltmann-Meyer S., Steiner D., Schneidereit D., Friedrich O., Grüneboom A., Amouei H., Wajant H., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
    A New Printable Alginate/Hyaluronic Acid/Gelatin Hydrogel Suitable for Biofabrication of In Vitro and In Vivo Metastatic Melanoma Models
    In: Advanced Functional Materials (2021)
    ISSN: 1616-301X
    DOI: 10.1002/adfm.202107993
  • Schneidereit D., Broellochs A., Ritter P., Kreiß L., Mokhtari Z., Beilhack A., Krönke G., Ackermann J., Faas M., Grüneboom A., Schürmann S., Friedrich O.:
    An advanced optical clearing protocol allows label-free detection of tissue necrosis via multiphoton microscopy in injured whole muscle
    In: Theranostics 11 (2021), S. 2876-2891
    ISSN: 1838-7640
    DOI: 10.7150/thno.51558
  • Shafiee A., Cavalcanti A., Saidy NT., Schneidereit D., Friedrich O., Ravichandran A., De-Juan-Pardo EM., Hutmacher DW.:
    Convergence of 3D printed biomimetic wound dressings and adult stem cell therapy.
    In: Biomaterials 268 (2021), S. 120558
    ISSN: 0142-9612
    DOI: 10.1016/j.biomaterials.2020.120558
  • Spörrer M., Kah DT., Gerum R., Reischl B., Huraskin D., Dessalles CA., Schneider W., Goldmann W., Herrmann H., Thievessen I., Clemen CS., Friedrich O., Hashemolhosseini S., Schröder R., Fabry B.:
    The desmin mutation R349P increases contractility and fragility of stem cell-generated muscle micro-tissues
    In: Neuropathology and Applied Neurobiology (2021)
    ISSN: 0305-1846
    DOI: 10.1111/nan.12784
  • Vielreicher M., Bozec A., Schett G., Friedrich O.:
    Murine Metatarsus Bone and Joint Collagen-I Fiber Morphologies and Networks Studied With SHG Multiphoton Imaging
    In: Frontiers in Bioengineering and Biotechnology 9 (2021), Art.Nr.: 608383
    ISSN: 2296-4185
    DOI: 10.3389/fbioe.2021.608383
  • Zimmermann T., Gebhardt L., Kreiß L., Schneider C., Arndt S., Karrer S., Friedrich O., Fischer MJM., Boßerhoff AK.:
    Acidified nitrite contributes to the antitumor effect of cold atmospheric plasma on melanoma cells
    In: International Journal of Molecular Sciences 22 (2021), Art.Nr.: 3757
    ISSN: 1422-0067
    DOI: 10.3390/ijms22073757

2020

  • Carullo G., Mazzotta S., Koch AM., Hartmann K., Friedrich O., Gilbert D., Vega-Holm M., Schneider-Stock R., Aiello F.:
    New oleoyl hybrids of natural antioxidants: Synthesis and in vitro evaluation as inducers of apoptosis in colorectal cancer cells
    In: Antioxidants 9 (2020), S. 1-16
    ISSN: 2076-3921
    DOI: 10.3390/antiox9111077
  • Distler T., Solisito A., Schneidereit D., Friedrich O., Detsch R., Boccaccini AR.:
    3D printed oxidized alginate-gelatin bioink provides guidance for C2C12 muscle precursor cell orientation and differentiation via shear stress during bioprinting
    In: Biofabrication 12 (2020), Art.Nr.: ARTN 045005
    ISSN: 1758-5082
    DOI: 10.1088/1758-5090/ab98e4
  • Fey C., Betz J., Rosenbaum C., Kralisch D., Vielreicher M., Friedrich O., Metzger M., Zdzieblo D.:
    Bacterial nanocellulose as novel carrier for intestinal epithelial cells in drug delivery studies
    In: Materials Science and Engineering C 109 (2020), Art.Nr.: 110613
    ISSN: 0928-4931
    DOI: 10.1016/j.msec.2019.110613
  • Fröhlich T., Mai C., Bogautdinov RP., Morozkina SN., Shavva AG., Friedrich O., Gilbert D., Tsogoeva S.:
    Synthesis of Tamoxifen-Artemisinin and Estrogen-Artemisinin Hybrids Highly Potent Against Breast and Prostate Cancer
    In: ChemMedChem (2020)
    ISSN: 1860-7179
    DOI: 10.1002/cmdc.202000174
  • Hazur J., Detsch R., Karakaya E., Kaschta J., Teßmar J., Schneidereit D., Friedrich O., Schubert DW., Boccaccini AR.:
    Improving alginate printability for biofabrication: establishment of a universal and homogeneous pre-crosslinking technique
    In: Biofabrication 12 (2020), Art.Nr.: 045004
    ISSN: 1758-5082
    DOI: 10.1088/1758-5090/ab98e5
  • Juia T., Horch RE., Grüner J., Schmid R., Kengelbach-Weigand A., Schubert DW., Werner S., Schneidereit D., Friedrich O., Ludolph I.:
    Size matters-in vitro behaviour of human fibroblasts on textured silicone surfaces with different pore sizes
    In: Journal of Materials Science: Materials in Medicine (2020)
    ISSN: 0957-4530
    DOI: 10.1007/s10856-020-6360-5
    URL: https://link.springer.com/article/10.1007/s10856-020-6360-5
  • Kreiß L., Thoma OM., Dilipkumar A., Carlé BE., Longequeue P., Kunert T., Rath T., Hildner K., Neufert C., Neurath M., Friedrich O., Schürmann S., Waldner MJ., Vieth M.:
    Label-Free In Vivo Histopathology of Experimental Colitis via 3-Channel Multiphoton Endomicroscopy
    In: Gastroenterology (2020)
    ISSN: 0016-5085
    DOI: 10.1053/j.gastro.2020.05.081
  • No YJ., Tarafder S., Reischl B., Ramaswamy Y., Dunstan CR., Friedrich O., Lee CH., Zreiqat H.:
    High-Strength Fiber-Reinforced Composite Hydrogel Scaffolds as Biosynthetic Tendon Graft Material
    In: ACS Biomaterials Science and Engineering 6 (2020), S. 1887-1898
    ISSN: 2373-9878
    DOI: 10.1021/acsbiomaterials.9b01716
  • Pollmann C., Haug M., Reischl B., Prölß G., Pöschel T., Rupitsch S., Clemen CS., Schröder R., Friedrich O.:
    Growing old too early: Skeletal muscle single fiber biomechanics in ageing r349p desmin knock-in mice using the myorobot technology
    In: International Journal of Molecular Sciences 21 (2020), S. 1-18
    ISSN: 1422-0067
    DOI: 10.3390/ijms21155501
  • Ritter P., Bye LJ., Finol-Urdaneta RK., Lesko C., Adams DJ., Friedrich O., Gilbert D.:
    A method for high-content functional imaging of intracellular calcium responses in gelatin-immobilized non-adherent cells
    In: Experimental Cell Research 395 (2020), Art.Nr.: 112210
    ISSN: 0014-4827
    DOI: 10.1016/j.yexcr.2020.112210
  • Schwappacher R., Schink K., Sologub S., Dieterich W., Reljic D., Friedrich O., Herrmann HJ., Neurath M., Zopf Y.:
    Physical activity and advanced cancer: evidence of exercise-sensitive genes regulating prostate cancer cell proliferation and apoptosis
    In: The Journal of Physiology (2020)
    ISSN: 0022-3751
    DOI: 10.1113/JP279150
  • Simon N., Sperber C., Voigtländer C., Born J., Gilbert D., Seyferth S., Lee G., Kappes B., Friedrich O.:
    Improved stability of polyclonal antibodies: A case study with lyophilization-conserved antibodies raised against epitopes from the malaria parasite Plasmodium falciparum
    In: European Journal of Pharmaceutical Sciences 142 (2020), Art.Nr.: 105086
    ISSN: 0928-0987
    DOI: 10.1016/j.ejps.2019.105086
  • Taeger CD., Friedrich O., Horch RE., Distler C., Kengelbach-Weigand A., Wenzel C., Prantl L., Präbst K.:
    Tissue Viability of Free Flaps after Extracorporeal Perfusion Using a Modified Hydroxyethyl Starch Solution
    In: Journal of Clinical Medicine 9 (2020)
    ISSN: 2077-0383
    DOI: 10.3390/jcm9123929
  • Weizel A., Distler T., Schneidereit D., Friedrich O., Bräuer L., Paulsen F., Detsch R., Boccaccini AR., Budday S., Seitz H.:
    Complex mechanical behavior of human articular cartilage and hydrogels for cartilage repair
    In: Acta Biomaterialia (2020)
    ISSN: 1742-7061
    DOI: 10.1016/j.actbio.2020.10.025
    URL: https://www.sciencedirect.com/science/article/pii/S1742706120306140

2019

  • Aschenbrenner D., Friedrich O., Gilbert D.:
    3D printed lab-on-a-chip platform for chemical stimulation and parallel analysis of ion channel function
    In: Micromachines 10 (2019), Art.Nr.: 548
    ISSN: 2072-666X
    DOI: 10.3390/mi10080548
  • Capci Karagöz A., Leidenberger M., Hahn F., Friedrich O., Hampel F., Marschall M., Kappes B., Tsogoeva S.:
    Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities
    In: Bioorganic & Medicinal Chemistry 27 (2019), S. 110-115
    ISSN: 0968-0896
    DOI: 10.1016/j.bmc.2018.11.018
  • Dilipkumar A., Al-Shemmary A., Kreiß L., Cvecek K., Carlé BE., Knieling F., Menezes JG., Thoma OM., Schmidt M., Neurath M., Waldner M., Friedrich O., Schürmann S.:
    Label-Free Multiphoton Endomicroscopy for Minimally Invasive In Vivo Imaging
    In: Advanced Science 6 (2019), Art.Nr.: 1801735
    ISSN: 2198-3844
    DOI: 10.1002/advs.201801735
  • Friedrich O., Haug M., Reischl B., Prölß G., Kiriaev L., Head SI., Reid MB.:
    Single muscle fibre biomechanics and biomechatronics – The challenges, the pitfalls and the future
    In: International Journal of Biochemistry and Cell Biology 114 (2019), Art.Nr.: 105563
    ISSN: 1357-2725
    DOI: 10.1016/j.biocel.2019.105563
  • Friedrich O., Merten AL., Schneidereit D., Guo Y., Schürmann S., Martinac B.:
    Stretch in Focus: 2D Inplane Cell Stretch Systems for Studies of Cardiac Mechano-Signaling
    In: Frontiers in Bioengineering and Biotechnology 7 (2019)
    ISSN: 2296-4185
    DOI: 10.3389/fbioe.2019.00055
  • Gilbert D., Abolpour Mofrad S., Friedrich O., Wiest J.:
    Proliferation characteristics of cells cultured under periodic versus static conditions.
    In: Cytotechnology 71 (2019), S. 443-452
    ISSN: 0920-9069
    DOI: 10.1007/s10616-018-0263-z
  • Haug M., Meyer C., Reischl B., Prölß G., Nübler S., Schürmann S., Schneidereit D., Heckel M., Pöschel T., Rupitsch S., Friedrich O.:
    MyoRobot 2.0: An advanced biomechatronics platform for automated, environmentally controlled skeletal muscle single fiber biomechanics assessment employing inbuilt real-time optical imaging
    In: Biosensors and Bioelectronics 138 (2019), Art.Nr.: 111284
    ISSN: 0956-5663
    DOI: 10.1016/j.bios.2019.04.052
  • Haug M., Meyer C., Reischl B., Prölß G., Vetter K., Iberl J., Nübler S., Schürmann S., Rupitsch S., Heckel M., Pöschel T., Winter L., Herrmann H., Clemen CS., Schröder R., Friedrich O.:
    The MyoRobot technology discloses a premature biomechanical decay of skeletal muscle fiber bundles derived from R349P desminopathy mice
    In: Scientific Reports 9 (2019), Art.Nr.: 10769
    ISSN: 2045-2322
    DOI: 10.1038/s41598-019-46723-6
  • Kahl M., Gertig M., Hoyer P., Friedrich O., Gilbert D.:
    Ultra-low-cost 3D bioprinting: Modification and application of an off-the-shelf desktop 3D-printer for biofabrication
    In: Frontiers in Bioengineering and Biotechnology 7 (2019), Art.Nr.: 184
    ISSN: 2296-4185
    DOI: 10.3389/fbioe.2019.00184
  • Kreiß L., Hohmann M., Klämpfl F., Schürmann S., Dehghani F., Schmidt M., Friedrich O., Büchler L.:
    Diffuse reflectance spectroscopy and Raman spectroscopy for label-free molecular characterization and automated detection of human cartilage and subchondral bone
    In: Sensors and Actuators B-Chemical 301 (2019), Art.Nr.: 127121
    ISSN: 0925-4005
    DOI: 10.1016/j.snb.2019.127121
  • Latronico N., Friedrich O.:
    Electrophysiological investigations of peripheral nerves and muscles: a method for looking at cell dysfunction in the critically ill patients
    In: Critical Care 23 (2019)
    ISSN: 1466-609X
    DOI: 10.1186/s13054-019-2331-y
  • Li JJ., Dunstan C., Entezari A., Li Q., Steck R., Saifzadeh S., Sadeghpour A., Field JR., Akey A., Vielreicher M., Friedrich O., Esfahani SI., Zreiqat H.:
    A novel bone substitute with high bioactivity, strength, and porosity for repairing large and load-bearing bone defects
    In: Advanced Healthcare Materials (2019), Art.Nr.: e1801298
    ISSN: 2192-2640
    DOI: 10.1002/adhm.201801298
  • Lopez Posadas R., Fastancz P., Martínez-Sánchez LdC., Panteleev-Ivlev J., Thonn V., Kisseleva T., Becker LS., Schulz-Kuhnt A., Zundler S., Wirtz S., Atreya R., Carlé BE., Friedrich O., Schürmann S., Waldner M., Neufert C., Brakebusch CH., Bergö MO., Neurath M., Atreya I.:
    Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice
    In: Gastroenterology 157 (2019), S. 1293-1309
    ISSN: 0016-5085
    DOI: 10.1053/j.gastro.2019.07.007
  • Muthumbi AK., Chaware A., Kim K., Zhou KC., Konda PC., Chen RY., Judkewitz B., Erdmann A., Kappes B., Horstmeyer R.:
    Learned sensing: jointly optimized microscope hardware for accurate image classification
    In: Biomedical Optics Express 10 (2019), S. 6351-6369
    ISSN: 2156-7085
    DOI: 10.1364/BOE.10.006351
  • Poettler M., Fliedner A., Bergmann J., Bui LK., Mühlberger M., Braun C., Graw M., Janko C., Friedrich O., Alexiou C., Lyer S.:
    Magnetic Tissue Engineering of the Vocal Fold Using Superparamagnetic Iron Oxide Nanoparticles
    In: Tissue Engineering: Parts A, B, and C (2019)
    ISSN: 1937-3368
    DOI: 10.1089/ten.tea.2019.0009
  • Schmitt M., Friedrich O., Gilbert D.:
    Portoporator©: A portable low-cost electroporation device for gene transfer to cultured cells in biotechnology, biomedical research and education
    In: Biosensors and Bioelectronics 131 (2019), S. 95-103
    ISSN: 0956-5663
    DOI: 10.1016/j.bios.2019.02.024
  • Steinmann S., Kunze P., Hampel C., Eckstein M., Bertram Bramsen J., Muenzner JK., Carlé BE., Ndreshkjana B., Kemenes S., Gasparini P., Friedrich O., Andersen C., Geppert C., Wang S., Eyupoglu I., Bäuerle T., Hartmann A., Schneider-Stock R.:
    DAPK1 loss triggers tumor invasion in colorectal tumor cells
    In: Cell Death & Disease 10 (2019), Art.Nr.: 895
    ISSN: 2041-4889
    DOI: 10.1038/s41419-019-2122-z
  • Von Bomhard A., Elsaesser A., Riepl R., Pippich K., Faust J., Schwarz S., Körber L., Breiter R., Rotter N.:
    Cartilage regeneration using decellularized cartilage matrix: Long-term comparison of subcutaneous and intranasal placement in a rabbit model
    In: Journal of Cranio-Maxillofacial Surgery 47 (2019), S. 682-694
    ISSN: 1010-5182
    DOI: 10.1016/j.jcms.2019.01.010
  • Çapcı A., Lorion MM., Wang H., Simon N., Leidenberger M., Borges Silva MC., Moreira DR., Zhu Y., Meng Y., Chen JY., Lee YM., Friedrich O., Kappes B., Wang J., Ackermann L., Tsogoeva S.:
    Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria
    In: Angewandte Chemie International Edition (2019)
    ISSN: 1433-7851
    DOI: 10.1002/anie.201907224

2018

  • Capci Karagöz A., Reiter C., Seo EJ., Gruber L., Hahn F., Leidenberger M., Klein V., Hampel F., Friedrich O., Marschall M., Kappes B., Efferth T., Tsogoeva S.:
    Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin
    In: Bioorganic & Medicinal Chemistry 26 (2018), S. 3610-3618
    ISSN: 0968-0896
    DOI: 10.1016/j.bmc.2018.05.041
  • Friedrich O., Diermeier S., Larsson L.:
    Weak by the machines: muscle motor protein dysfunction - a side effect of intensive care unit treatment.
    In: Acta Physiologica 222 (2018), Art.Nr.: e12885
    ISSN: 1748-1708
    DOI: 10.1111/apha.12885
  • Fröhlich T., Hahn F., Belmudes L., Leidenberger M., Friedrich O., Kappes B., Coute Y., Marschall M., Tsogoeva S.:
    Synthesis of Artemisinin-Derived Dimers, Trimers and Dendrimers: Investigation of Their Antimalarial and Antiviral Activities Including Putative Mechanisms of Action
    In: Chemistry - A European Journal 24 (2018), S. 8103-8113
    ISSN: 0947-6539
    DOI: 10.1002/chem.201800729
  • Fröhlich T., Kiss A., Wolfling J., Mernyak E., Kulmany AE., Minorics R., Zupko I., Leidenberger M., Friedrich O., Kappes B., Hahn F., Marschall M., Schneider G., Tsogoeva S.:
    Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P-falciparum, and Cervical and Breast Cancer
    In: ACS Medicinal Chemistry Letters 9 (2018), S. 1128-1133
    ISSN: 1948-5875
    DOI: 10.1021/acsmedchemlett.8b00381
  • Fröhlich T., Reiter C., Saeed MEM., Hutterer C., Hahn F., Leidenberger M., Friedrich O., Kappes B., Marschall M., Efferth T., Tsogoeva S.:
    Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents
    In: ACS Medicinal Chemistry Letters 9 (2018), S. 534-539
    ISSN: 1948-5875
    DOI: 10.1021/acsmedchemlett.7b00412
  • Haug M., Reischl B., Prölß G., Pollmann C., Buckert T., Keidel C., Schürmann S., Hock M., Rupitsch S., Heckel M., Pöschel T., Scheibel T., Haynl C., Kiriaev L., Head SI., Friedrich O.:
    The MyoRobot: A novel automated biomechatronics system to assess voltage/Ca2+ biosensors and active/passive biomechanics in muscle and biomaterials
    In: Biosensors and Bioelectronics 102 (2018), S. 589-599
    ISSN: 0956-5663
    DOI: 10.1016/j.bios.2017.12.003
  • Knieling F., Menezes JG., Claussen J., Schwarz M., Neufert C., Fahlbusch FB., Rath T., Thoma OM., Kramer V., Menchicchi B., Kersten C., Scheibe K., Schürmann S., Carlé BE., Rascher W., Neurath M., Ntziachristos V., Waldner M.:
    Raster-Scanning Optoacoustic Mesoscopy for Gastrointestinal Imaging at High Resolution
    In: Gastroenterology 154 (2018), S. 807-809.e3
    ISSN: 0016-5085
    DOI: 10.1053/j.gastro.2017.11.285
  • Li JJ., Akey A., Dunstan C., Vielreicher M., Friedrich O., Bell DC., Zreiqat H.:
    Effects of Material-Tissue Interactions on Bone Regeneration Outcomes Using
    Baghdadite Implants in a Large Animal Model

    In: Advanced Healthcare Materials 7 (2018), Art.Nr.: e1800218
    ISSN: 2192-2640
    DOI: 10.1002/adhm.201800218
  • Milanos S., Künzel K., Gilbert D., Janzen D., Sasi M., Büttner A., Frimurer TM., Villmann C.:
    Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation.
    In: Biological Chemistry (2018)
    ISSN: 1431-6730
    DOI: 10.1515/hsz-2017-0262
  • Reiling SJ., Krohne G., Friedrich O., Geary TG., Rohrbach P.:
    Chloroquine exposure triggers distinct cellular responses in sensitive versus resistant Plasmodium falciparum parasites
    In: Scientific Reports 8 (2018), Art.Nr.: 11137
    ISSN: 2045-2322
    DOI: 10.1038/s41598-018-29422-6
  • Reisbeck M., Richter L., Helou MJ., Arlinghaus S., Anton B., van Dommelen I., Nitzsche M., Bassler M., Kappes B., Friedrich O., Hayden O.:
    Hybrid integration of scalable mechanical and magnetophoretic focusing for magnetic flow cytometry
    In: Biosensors and Bioelectronics 109 (2018), S. 98-108
    ISSN: 0956-5663
    DOI: 10.1016/j.bios.2018.02.046
  • Scharin-Mehlmann M., Häring A., Rommel M., Dirnecker T., Friedrich O., Frey L., Gilbert D.:
    Nano- and micro-patterned S-, H-, and X-PDMS for cell-based applications: Comparison of wettability, roughness, and cell-derived parameters
    In: Frontiers in Bioengineering and Biotechnology 6 (2018), Art.Nr.: 51
    ISSN: 2296-4185
    DOI: 10.3389/fbioe.2018.00051
  • Schneidereit D., Nübler S., Prölß G., Reischl B., Schürmann S., Müller OJ., Friedrich O.:
    Optical prediction of single muscle fiber force production using a combined biomechatronics and second harmonic generation imaging approach
    In: Light: Science & Applications 7 (2018), Art.Nr.: 79
    ISSN: 2047-7538
    DOI: 10.1038/s41377-018-0080-3
  • Schneidereit D., Schürmann S., Friedrich O.:
    PiezoGRIN: A High-Pressure Chamber Incorporating GRIN Lenses for High-Resolution 3D-Microscopy of living Cells and Tissues
    In: Advanced Science (2018), Art.Nr.: 1801453
    ISSN: 2198-3844
    DOI: 10.1002/advs.201801453
  • Schneidereit D., Tschernich J., Friedrich O., Scharin-Mehlmann M., Gilbert D.:
    3D-Printed Reusable Cell Culture Chamber with Integrated Electrodes for Electrical Stimulation and Parallel Microscopic Evaluation
    In: 3D Printing and Additive Manufacturing 5 (2018), S. 115-125
    ISSN: 2329-7662
    DOI: 10.1089/3dp.2017.0103
  • Simon N., Friedrich O., Kappes B.:
    Quantification of human complement factor H binding to asexual malaria blood stages by an enzyme-linked immunosorbent assay
    In: Vaccine 36 (2018), S. 1545-1547
    ISSN: 0264-410X
    DOI: 10.1016/j.vaccine.2018.01.080
  • Ugele M., Weniger M., Leidenberger M., Huang Y., Bassler M., Friedrich O., Kappes B., Hayden O., Richter L.:
    Label-free, high-throughput detection of P-falciparum infection in sphered erythrocytes with digital holographic microscopy
    In: Lab on A Chip 18 (2018), S. 1704-1712
    ISSN: 1473-0197
    DOI: 10.1039/c8lc00350e
  • Ugele M., Weniger M., Stanzel M., Bassler M., Krause S., Friedrich O., Hayden O., Richter L.:
    Label-Free High-Throughput Leukemia Detection by Holographic Microscopy
    In: Advanced Science 5 (2018)
    ISSN: 2198-3844
    DOI: 10.1002/advs.201800761
  • Vielreicher M., Kralisch D., Sternal F., Arkudas A., Friedrich O., Völkl S.:
    Bacterial nanocellulose stimulates mesenchymal stem cell expansion and formation of stable collagen-I networks as a novel biomaterial in tissue engineering
    In: Scientific Reports 8 (2018)
    ISSN: 2045-2322
    DOI: 10.1038/s41598-018-27760-z
  • Walzik MP., Vollmar V., Lachnit T., Dietz H., Haug S., Bachmann H., Fath M., Aschenbrenner D., Mofrad SA., Friedrich O., Gilbert D.:
    Corrigendum to "A portable low-cost long-term live-cell imaging platform for biomedical research and education" [Biosens. Bioelectron. 64 (2015) 639-649].
    In: Biosensors and Bioelectronics 99 (2018), S. 683
    ISSN: 0956-5663
    DOI: 10.1016/j.bios.2017.08.021

2017

  • Bock C., Gangajji P., Bönisch S., Bauer W., Hutterer C., Leidenberger M., Friedrich O., Marschall M., Kappes B., Görling A., Tsogoeva S.:
    Deeper Insight into the Six-Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products.
    In: ChemistryOpen 6 (2017), S. 364-374
    ISSN: 2191-1363
    DOI: 10.1002/open.201700005
  • Diermeier S., Buttgereit A., Schürmann S., Winter L., Xu H., Murphy RM., Clemen CS., Schröder R., Friedrich O.:
    Preaged remodeling of myofibrillar cytoarchitecture in skeletal muscle expressing R349P mutant desmin
    In: Neurobiology of Aging 58 (2017), S. 77-87
    ISSN: 0197-4580
    DOI: 10.1016/j.neurobiolaging.2017.06.001
  • Diermeier S., Iberl J., Vetter K., Haug M., Pollmann C., Reischl B., Buttgereit A., Schürmann S., Spörrer M., Goldmann W., Fabry B., Elhamine F., Stehle R., Pfitzer G., Winter L., Clemen CS., Herrmann H., Schröder R., Friedrich O.:
    Early signs of architectural and biomechanical failure in isolated myofibers and immortalized myoblasts from desmin-mutant knock-in mice
    In: Scientific Reports 7 (2017), S. 1391
    ISSN: 2045-2322
    DOI: 10.1038/s41598-017-01485-x
  • Friedrich O., Head S.:
    Quantitative Ratiometric Ca(2+) Imaging to Assess Cell Viability.
    In: Methods in Molecular Biology 1601 (2017), S. 171-193
    ISSN: 1064-3745
    DOI: 10.1007/978-1-4939-6960-9_14
  • Friedrich O., Schneidereit D., Nikolaev YA., Nikolova-Krstevski V., Schürmann S., Wirth-Hücking A., Merten AL., Fatkin D., Martinac B.:
    Adding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular biomechanics and mechano-signaling.
    In: Progress in biophysics and molecular biology (2017)
    ISSN: 1873-1732
    DOI: 10.1016/j.pbiomolbio.2017.06.011
  • Fröhlich T., Reiter C., Ibrahim MM., Beutel J., Hutterer C., Zeitträger I., Bahsi H., Leidenberger M., Friedrich O., Kappes B., Efferth T., Marschall M., Tsogoeva S.:
    Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells
    In: ACS Omega 2 (2017), S. 2422-2431
    ISSN: 2470-1343
    DOI: 10.1021/acsomega.7b00310
  • Gilbert D.:
    Maßgeschneiderte Methoden und Technologien für high content imaging
    In: BioSpektrum 23. Jahrgang (2017), S. 286-288
    ISSN: 0947-0867
    DOI: 10.1007/s12268-017-0798-0
  • Gilbert D., Friedrich O., Schneidereit D., Meier JC., Kraus L.:
    Step-by-step guide to building an inexpensive 3D printed motorized positioning stage for automated high-content screening microscopy.
    In: Biosensors and Bioelectronics 92 (2017), S. 472-481
    ISSN: 0956-5663
    DOI: 10.1016/j.bios.2016.10.078
  • Kravic B., Harbauer AB., Romanello V., Simeone L., Vögtle FN., Kaiser T., Straubinger M., Huraskin D., Böttcher M., Cerqua C., Martin ED., Poveda-Huertes D., Buttgereit A., Rabalski AJ., Heuss D., Rudolf R., Friedrich O., Litchfield D., Marber M., Salviati L., Mougiakakos D., Neuhuber W., Sandri M., Meisinger C., Hashemolhosseini S.:
    In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy
    In: Autophagy (2017), S. 1-65
    ISSN: 1554-8627
    DOI: 10.1080/15548627.2017.1403716
  • Leidenberger M., Voigtländer C., Simon N., Kappes B.:
    Green I-Based Fluorescence Assay to Assess Cell Viability of Malaria Parasites for Routine Use in Compound Screening.
    In: Methods in Molecular Biology 1601 (2017), S. 97-110
    ISSN: 1064-3745
    DOI: 10.1007/978-1-4939-6960-9_9
  • Menzner AK., Abolpour Mofrad S., Friedrich O., Gilbert D.:
    Corrigendum to "Towards in vitro DT/DNT testing: Assaying chemical susceptibility in early differentiating NT2 cells" [Toxicology 338 (2015) 69-76].
    In: Toxicology 389 (2017), S. 108
    ISSN: 1879-3185
    DOI: 10.1016/j.tox.2017.08.001
  • Resheq YJ., Menzner AK., Bosch J., Tickle J., Li KK., Wilhelm A., Hepburn E., Murihead G., Ward ST., Curbishley SM., Zimmermann HW., Bruns T., Gilbert D., Tripal P., Mackensen A., Adams DH., Weston CJ.:
    Impaired Transmigration of Myeloid-Derived Suppressor Cells across Human Sinusoidal Endothelium Is Associated with Decreased Expression of CD13
    In: Journal of Immunology (2017)
    ISSN: 0022-1767
    DOI: 10.4049/jimmunol.1600466
  • Taeger CD., Friedrich O., Horch RE., Drechsler C., Weigand A., Hopf F., Geppert C., Münch F., Birkholz T., Wenzel C., Geis S., Prantl L., Buchholz R., Präbst K.:
    Extracorporeal perfusion - reduced to a one-way infusion.
    In: Clinical hemorheology and microcirculation (2017)
    ISSN: 1875-8622
    DOI: 10.3233/CH-170298
  • Vielreicher M., Friedrich O.:
    Assessment of Population and ECM Production Using Multiphoton Microscopy as an Indicator of Cell Viability.
    In: Methods in Molecular Biology 1601 (2017), S. 243-255
    ISSN: 1064-3745
    DOI: 10.1007/978-1-4939-6960-9_19
  • Waldner M., Rath T., Schürmann S., Bojarski C., Atreya R.:
    Imaging of Mucosal Inflammation: Current Technological Developments, Clinical Implications, and Future Perspectives
    In: Frontiers in Immunology 8 (2017)
    ISSN: 1664-3224
    DOI: 10.3389/fimmu.2017.01256
  • Wrosch JK., Volbers B., Gölitz P., Gilbert D., Schwab S., Dörfler A., Kornhuber J., Groemer TW.:
    Corrigendum: Feasibility and Diagnostic Accuracy of Ischemic Stroke Territory Recognition Based on Two-dimensional Projections of Three-dimensional Diffusion MRI Data
    In: Frontiers in Neurology 8 (2017), S. 56
    ISSN: 1664-2295
    DOI: 10.3389/fneur.2017.00056

2016

  • Abolpour Mofrad S., Künzel K., Friedrich O., Gilbert D.:
    Optimizing neuronal differentiation of human pluripotent NT2 stem cells in monolayer cultures.
    In: Development, growth & differentiation 58 (2016), S. 664-676
    ISSN: 1440-169X
    DOI: 10.1111/dgd.12323
  • Chernavskaia O., Heuke S., Friedrich O., Schürmann S., Atreya R., Stallmach A., Neurath M., Waldner M., Petersen I., Schmitt M., Bocklitz T., Popp J., Vieth M.:
    Beyond endoscopic assessment in inflammatory bowel disease: real-time histology of disease activity by non-linear multimodal imaging.
    In: Scientific Reports 6 (2016), S. 29239
    ISSN: 2045-2322
    DOI: 10.1038/srep29239
  • Dakhil H., Gilbert D., Malhotra D., Limmer A., Engelhardt H., Amtmann A., Hansmann J., Hübner H., Buchholz R., Friedrich O., Wierschem A.:
    Measuring average rheological quantities of cell monolayers in the linear viscoelastic regime
    In: Rheologica Acta 55 (2016), S. 527-536
    ISSN: 0035-4511
    DOI: 10.1007/s00397-016-0936-5
  • Diermeier S., Buttgereit A., Clemen C., Schröder R., Friedrich O.:
    Aging-related progressive skeletal muscle weakness in mutant DesR349P muscles: a matter of compromised cytoarchitecture
    In: Acta Physiologica 216 (2016)
    ISSN: 1748-1708
  • Gilbert D., Stebbing MJ., Künzel K., Murphy RM., Zacharewicz E., Buttgereit A., Stokes L., Adams DJ., Friedrich O.:
    Store-Operated Ca(2+) Entry (SOCE) and Purinergic Receptor-Mediated Ca(2+) Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation.
    In: Frontiers in Molecular Neuroscience 9 (2016), S. 111
    ISSN: 1662-5099
    DOI: 10.3389/fnmol.2016.00111
  • Künzel K., Friedrich O., Gilbert D.:
    A Recombinant Human Pluripotent Stem Cell Line Stably Expressing Halide-Sensitive YFP-I152L for GABAAR and GlyR-Targeted High-Throughput Drug Screening and Toxicity Testing.
    In: Frontiers in Molecular Neuroscience 9 (2016), Art.Nr.: 51
    ISSN: 1662-5099
    DOI: 10.3389/fnmol.2016.00051
  • Larsson L., Friedrich O.:
    Critical Illness Myopathy (CIM) and Ventilator-Induced Diaphragm Muscle Dysfunction (VIDD): Acquired Myopathies Affecting Contractile Proteins.
    In: Comprehensive Physiology 7 (2016), S. 105-112
    ISSN: 2040-4603
    DOI: 10.1002/cphy.c150054
  • Olah T., Bodnar D., Toth A., Vincze J., Fodor J., Reischl B., Kovacs A., Ruzsnavszky O., Dienes B., Szentesi P., Friedrich O., Csernoch L.:
    Cannabinoid signalling inhibits sarcoplasmic Ca(2+) release and regulates excitation-contraction coupling in mammalian skeletal muscle.
    In: The Journal of Physiology 594 (2016), S. 7381-7398
    ISSN: 0022-3751
    DOI: 10.1113/JP272449
  • Reisbeck M., Helou MJ., Richter L., Kappes B., Friedrich O., Hayden O.:
    Magnetic fingerprints of rolling cells for quantitative flow cytometry in whole blood.
    In: Scientific Reports 6 (2016), S. 32838
    ISSN: 2045-2322
    DOI: 10.1038/srep32838
  • Schneidereit D., Vass H., Reischl B., Allen RJ., Friedrich O.:
    Calcium Sensitive Fluorescent Dyes Fluo-4 and Fura Red under Pressure: Behaviour of Fluorescence and Buffer Properties under Hydrostatic Pressures up to 200 MPa.
    In: PLoS ONE 11 (2016), S. e0164509
    ISSN: 1932-6203
    DOI: 10.1371/journal.pone.0164509
  • Schürmann S., Wagner S., Herlitze S., Fischer C., Gumbrecht S., Wirth-Hücking A., Prölß G., Lautscham L., Fabry B., Goldmann W., Nikolova-Krstevski V., Martinac B., Friedrich O.:
    The IsoStretcher: An isotropic cell stretch device to study mechanical biosensor pathways in living cells.
    In: Biosensors and Bioelectronics 81 (2016), S. 363-72
    ISSN: 0956-5663
    DOI: 10.1016/j.bios.2016.03.015
  • Spitzer P., Condic M., Herrmann M., Oberstein T., Scharin-Mehlmann M., Gilbert D., Friedrich O., Groemer T., Kornhuber J., Lang R., Maler JM.:
    Amyloidogenic amyloid-?-peptide variants induce microbial agglutination and exert antimicrobial activity
    In: Scientific Reports 6 (2016), S. 32228
    ISSN: 2045-2322
    DOI: 10.1038/srep32228
  • Taeger C., Friedrich O., Drechsler C., Weigand A., Hobe F., Geppert C., Münch F., Birkholz T., Buchholz R., Horch RE., Präbst K., Buchholz R.:
    Hydroxyethyl starch solution for extracorporeal tissue perfusion
    In: Clinical hemorheology and microcirculation (2016)
    ISSN: 1875-8622
    DOI: 10.3233/CH-162049
  • Vielreicher M., Friedrich O.:
    Nichtinvasive Hochleistungstechnik zur Gewebeuntersuchung. Multiphotonen-Mikroskopie stellt Kollagen-I-Netzwerk in Knochen dar
    In: Orthopädie & Rheuma 16 (2016), S. 38-43
    ISSN: 1435-0017
    DOI: 10.1007/s15002-016-0984-3
    URL: https://www.springermedizin.de/multiphotonen-mikroskopie-stellt-kollagen-i-netzwerke-in-knochen/10854042

2015

  • Auernheimer V., Lautscham L., Leidenberger M., Friedrich O., Kappes B., Fabry B., Goldmann W.:
    Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission.
    In: Journal of cell science (2015)
    ISSN: 1477-9137
    DOI: 10.1242/jcs.172031
    URL: http://jcs.biologists.org/content/early/2015/07/31/jcs.172031
  • Clemen C., Stöckigt F., Strucksberg KH., Chevessier F., Winter L., Schütz J., Bauer R., Thorweihe JM., Wenzel D., Schlötzer-Schrehardt U., Rasche V., Krsmanovic P., Katus H., Rottbauer W., Just S., Müller OJ., Friedrich O., Meyer R., Herrmann H., Schrickel JW., Schröder R.:
    The toxic effect of R350P mutant desmin in striated muscle of man and mouse.
    In: Acta Neuropathologica 129 (2015), S. 297-315
    ISSN: 0001-6322
    DOI: 10.1007/s00401-014-1363-2
    URL: http://link.springer.com/article/10.1007%2Fs00401-014-1363-2
  • Dakhil H., Wierschem A., Gilbert D., Amtmann A., Hübner H., Buchholz R., Friedrich O.:
    Viscoelastic Measurements of Cells in a Rotational Rheometer
    In: Chemie Ingenieur Technik 87 (2015), S. 1106
    ISSN: 0009-286X
  • Friedrich O., Reid M., van den Berghe G., Vanhorebeek I., Hermans G., Rich MM., Larsson L.:
    The sick and the weak: Neuropathies/ myopathies in the critically ill
    In: Physiological Reviews 95 (2015), S. 1025-1109
    ISSN: 1522-1210
    DOI: 10.1152/physrev.00028.2014
  • Head SI., Chan S., Houweling PJ., Quinlan KGR., Murphy R., Wagner S., Friedrich O., North KN.:
    Altered Ca2+ Kinetics Associated with alpha-Actinin-3 Deficiency May Explain Positive Selection for ACTN3 Null Allele in Human Evolution
    In: PLoS Genetics 11 (2015), Art.Nr.: e1004862
    ISSN: 1553-7390
    DOI: 10.1371/journal.pgen.1004862
  • Künzel K., Abolpour Mofrad S., Friedrich O., Gilbert D.:
    Establishment and validation of recombinant cell lines for high-throughput DNT testing
    In: Acta Physiologica 213 (2015), S. 78-79
    ISSN: 1748-1708
    (anderer)
  • Menzner AK., Abolpour Mofrad S., Friedrich O., Gilbert D.:
    Towards in vitro DT/DNT testing: Assaying chemical susceptibility in early differentiating NT2 cells.
    In: Toxicology 338 (2015), S. 69-76
    ISSN: 0300-483X
    DOI: 10.1016/j.tox.2015.10.007
  • Reiter C., Fröhlich T., Gruber L., Hutterer C., Marschall M., Voigtländer C., Friedrich O., Kappes B., Efferth T., Tsogoeva S.:
    Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities.
    In: Bioorganic & medicinal chemistry (2015)
    ISSN: 1464-3391
    DOI: 10.1016/j.bmc.2015.07.048
    URL: http://www.sciencedirect.com/science/article/pii/S096808961500632X
  • Reiter C., Fröhlich T., Zeino M., Marschall M., Bahsi H., Leidenberger M., Friedrich O., Kappes B., Hampel F., Efferth T., Tsogoeva S.:
    New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids.
    In: European journal of medicinal chemistry 97 (2015), S. 164-72
    ISSN: 1768-3254
    DOI: 10.1016/j.ejmech.2015.04.053
    URL: http://www.sciencedirect.com/science/article/pii/S0223523415300179
  • Ritterhoff J., Völkers M., Seitz A., Spaich K., Gao E., Peppel K., Pleger S., Zimmermann W., Friedrich O., Fink R., Koch W., Katus H., Most P.:
    S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction.
    In: Molecular Therapy 23 (2015), S. 1320-30
    ISSN: 1525-0016
    DOI: 10.1038/mt.2015.93
    URL: http://www.nature.com/mt/journal/v23/n8/full/mt201593a.html
  • Sinner B., Friedrich O., Lindner R., Bundscherer A., Graf B.:
    Long-term NMDA receptor inhibition affects NMDA receptor expression and alters glutamatergic activity in developing rat hippocampal neurons.
    In: Toxicology 333 (2015), S. 147-55
    ISSN: 1879-3185
    DOI: 10.1016/j.tox.2015.04.017
    URL: http://www.sciencedirect.com/science/article/pii/S0300483X15000888
  • Taeger C., Friedrich O., Dragu A., Weigand A., Hobe F., Drechsler C., Geppert C., Arkudas A., Münch F., Buchholz R., Pollmann C., Schramm A., Birkholz T., Horch RE., Präbst K., Buchholz R.:
    Assessing viability of extracorporeal preserved muscle transplants using external field stimulation: a novel tool to improve methods prolonging bridge-to-transplantation time.
    In: Scientific Reports 5 (2015), S. 11956
    ISSN: 2045-2322
    DOI: 10.1038/srep11956
  • Vielreicher M., Gellner M., Rottensteiner U., Horch RE., Arkudas A., Friedrich O.:
    Multiphoton microscopy analysis of extracellular collagen I network formation by mesenchymal stem cells.
    In: Journal of Tissue Engineering and Regenerative Medicine 11 (2015), S. 2104-2115
    ISSN: 1932-7005
    DOI: 10.1002/term.2107
  • Wagner S., Schürmann S., Schüttler J., Hein S., Friedrich O.:
    Septic cardiomyopathy in rat LPS-induced endotoxemia: relative contribution of cellular diastolic Ca2+ removal pathways, myofibrillar biomechanics properties and action of the cardiotonic drug levosimendan
    In: Basic research in cardiology 110 (2015), S. 507
    ISSN: 1435-1803
    DOI: 10.1007/s00395-015-0507-4
    URL: http://link.springer.com/article/10.1007/s00395-015-0507-4
  • Walzik MP., Vollmar V., Lachnit T., Dietz H., Haug S., Bachmann H., Fath M., Aschenbrenner D., Abolpour Mofrad S., Friedrich O., Gilbert D.:
    A portable low-cost long-term live-cell imaging platform for biomedical research and education.
    In: Biosensors and Bioelectronics 64 (2015), S. 639-49
    ISSN: 0956-5663
    DOI: 10.1016/j.bios.2014.09.061
    URL: http://www.sciencedirect.com/science/article/pii/S0956566314007489
  • Wrosch JK., Volbers B., Gölitz P., Gilbert D., Schwab S., Dörfler A., Kornhuber J., Groemer TW.:
    Feasibility and Diagnostic Accuracy of Ischemic Stroke Territory Recognition Based on Two-Dimensional Projections of Three-Dimensional Diffusion MRI Data.
    In: Frontiers in Neurology (2015)
    ISSN: 1664-2295
    DOI: 10.3389/fneur.2015.00239

2014

  • Buttgereit A., Weber C., Friedrich O.:
    A novel quantitative morphometry approach to assess regeneration in dystrophic skeletal muscle.
    In: Neuromuscular Disorders 24 (2014), S. 596-603
    ISSN: 0960-8966
    DOI: 10.1016/j.nmd.2014.04.011
    URL: http://www.nmd-journal.com/article/S0960-8966%2814%2900113-8/abstract
  • Edwards JN., Weber C., Liu I., Reischl B., Most P., Wirth-Hücking A., Yi B., Friedrich O., Voelkers M., Buttgereit A., Lang R., Lee A., Polyak F., Von Wegner F., Cully TR.:
    IL-1α reversibly inhibits skeletal muscle ryanodine receptor a novel mechanism for critical illness myopathy?
    In: American journal of respiratory cell and molecular biology 50 (2014), S. 1096-1106
    ISSN: 1535-4989
    DOI: 10.1165/rcmb.2013-0059OC
  • Friedrich O.:
    'Set the controls...' - phenotype matching beyond genetics in muscular dystrophy
    In: Experimental physiology 99 (2014), S. 638-639
    ISSN: 1469-445X
    DOI: 10.1113/expphysiol.2014.077933
    URL: http://onlinelibrary.wiley.com/doi/10.1113/expphysiol.2014.077933/full
  • Friedrich O., Reiling S., Wunderlich J., Rohrbach P.:
    Assessment of Plasmodium falciparum PfMDR1 transport rates using Fluo-4.
    In: Journal of cellular and molecular medicine 18 (2014), S. 1851-62
    ISSN: 1582-4934
    DOI: 10.1111/jcmm.12313
    URL: http://onlinelibrary.wiley.com/doi/10.1111/jcmm.12313/abstract
  • Kolb T., Albert S., Haug M., Whyte G.:
    Optofluidic rotation of living cells for single-cell tomography
    In: Journal of Biophotonics 8 (2014), S. 239-246
    ISSN: 1864-063X
    DOI: 10.1002/jbio.201300196
  • Taskin S., Stumpf VI., Bachmann J., Weber C., Martignoni ME., Friedrich O.:
    Motor protein function in skeletal abdominal muscle of cachectic cancer patients.
    In: Journal of cellular and molecular medicine 18 (2014), S. 69-79
    ISSN: 1582-4934
    DOI: 10.1111/jcmm.12165
    URL: http://onlinelibrary.wiley.com/doi/10.1111/jcmm.12165/abstract;jsessionid=E5BDFC4245413F048ECA099352DF0B8B.f02t04

2013

  • Balansa W., Islam R., Fontaine F., Piggott A., Zhang H., Xiao X., Webb T., Gilbert D., Lynch J., Capon R.:
    Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia.
    In: Organic & biomolecular chemistry 11 (2013), S. 4695-701
    ISSN: 1477-0539
    DOI: 10.1039/c3ob40861b
  • Balansa W., Islam R., Gilbert D., Fontaine F., Xiao X., Zhang H., Piggott A., Lynch J., Capon R.:
    Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator.
    In: Bioorganic & medicinal chemistry 21 (2013), S. 4420-5
    ISSN: 1464-3391
    DOI: 10.1016/j.bmc.2013.04.061
  • Buttgereit A., Weber C., Garbe CS., Friedrich O.:
    From chaos to split-ups - SHG microscopy reveals a specific remodelling mechanism in ageing dystrophic muscle
    In: Journal of Pathology 229 (2013), S. 477-85
    ISSN: 0022-3417
    DOI: 10.1002/path.4136
  • Börner K., Niopek D., Cotugno G., Kaldenbach M., Pankert T., Willemsen J., Zhang X., Schürmann N., Mockenhaupt S., Serva A., Hiet M., Wiedtke E., Castoldi M., Starkuviene V., Erfle H., Gilbert D., Bartenschlager R., Boutros M., Binder M., Streetz K., Kräusslich H., Grimm D.:
    Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines.
    In: Nucleic Acids Research 41 (2013), S. e199
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkt836
  • Jung J., Weisenburger S., Albert S., Gilbert D., Friedrich O., Eulenburg V., Kornhuber J., Groemer TW.:
    Performance of scientific cameras with different sensor types in measuring dynamic processes in fluorescence microscopy.
    In: Microscopy research and technique 76 (2013), S. 835-43
    ISSN: 1097-0029
    DOI: 10.1002/jemt.22236
  • Kuhns S., Schmidt K., Reymann J., Gilbert D., Neuner A., Hub B., Carvalho R., Wiedemann P., Zentgraf H., Erfle H., Klingmüller U., Boutros M., Pereira G.:
    The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis.
    In: The Journal of Cell Biology 200 (2013), S. 505-22
    ISSN: 0021-9525
    DOI: 10.1083/jcb.201206013
  • Lang N., Münster S., Metzner C., Krauß P., Schürmann S., Lange J., Aifantis KE., Friedrich O., Fabry B.:
    Estimating the 3D pore size distribution of biopolymer networks from directionally biased data.
    In: Biophysical Journal 105 (2013), S. 1967-75
    ISSN: 0006-3495
    DOI: 10.1016/j.bpj.2013.09.038
    URL: http://www.sciencedirect.com/science/article/pii/S0006349513010862
  • Schürmann S., Försch S., Atreya R., Neumann H., Friedrich O., Neurath M., Waldner M.:
    Label-free imaging of inflammatory bowel disease using multiphoton microscopy.
    In: Gastroenterology 145 (2013), S. 514-6
    ISSN: 0016-5085
    DOI: 10.1053/j.gastro.2013.06.054
    URL: http://www.gastrojournal.org/article/S0016-5085%2813%2900998-0/fulltext
  • Talwar S., Lynch J., Gilbert D.:
    Fluorescence-based high-throughput functional profiling of ligand-gated ion channels at the level of single cells.
    In: PLoS ONE 8 (2013), S. e58479
    ISSN: 1932-6203
    DOI: 10.1371/journal.pone.0058479
  • Vielreicher M., Schürmann S., Detsch R., Schmidt M., Buttgereit A., Boccaccini AR., Friedrich O.:
    Taking a deep look: modern microscopy technologies to optimize the design and functionality of biocompatible scaffolds for tissue engineering in regenerative medicine
    In: Journal of the Royal Society Interface 10 (2013), S. 20130263
    ISSN: 1742-5689
    DOI: 10.1098/rsif.2013.0263
    URL: http://rsif.royalsocietypublishing.org/content/10/86/20130263

2012

  • Cully TR., Edwards JN., Friedrich O., Stephenson DG., Murphy RM., Launikonis BS.:
    Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca(2+) signaling in dystrophic mdx mouse muscle.
    In: American journal of physiology. Cell physiology 303 (2012), S. C567-76
    ISSN: 1522-1563
    DOI: 10.1152/ajpcell.00144.2012
    URL: http://ajpcell.physiology.org/content/303/5/C567
  • Friedrich O., Wagner S., Battle A., Schürmann S., Martinac B.:
    Mechano-regulation of the beating heart at the cellular level - Mechanosensitive channels in normal and diseased heart
    In: Progress in Biophysics & Molecular Biology 110 (2012), S. 226-238
    ISSN: 0079-6107
    DOI: 10.1016/j.pbiomolbio.2012.08.009
  • Garbe CS., Buttgereit A., Schürmann S., Friedrich O.:
    Automated multiscale morphometry of muscle disease from second harmonic generation microscopy using tensor-based image processing.
    In: IEEE transactions on bio-medical engineering 59 (2012), S. 39-44
    ISSN: 1558-2531
    DOI: 10.1109/TBME.2011.2167325
    URL: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6015536
  • Wagner S., Knipp S., Weber C., Hein S., Schinkel S., Walther A., Bekeredjian R., Müller OJ., Friedrich O.:
    The heart in Duchenne muscular dystrophy: early detection of contractile performance alteration.
    In: Journal of cellular and molecular medicine 16 (2012), S. 3028-36
    ISSN: 1582-4934
    DOI: 10.1111/j.1582-4934.2012.01630.x
    URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1582-4934.2012.01630.x/abstract

2011

  • Edwards JN., Blackmore D., Gilbert D., Murphy R., Launikonis BS.:
    Store-operated calcium entry remains fully functional in aged mouse skeletal muscle despite a decline in STIM1 protein expression.
    In: Aging Cell 10 (2011), S. 675-85
    ISSN: 1474-9718
    DOI: 10.1111/j.1474-9726.2011.00706.x
  • Gilbert D., Erdmann G., Zhang X., Fritzsche A., Demir K., Jaedicke A., Muehlenberg K., Wanker E., Boutros M.:
    A novel multiplex cell viability assay for high-throughput RNAi screening.
    In: PLoS ONE 6 (2011), S. e28338
    ISSN: 1932-6203
    DOI: 10.1371/journal.pone.0028338
  • Mohl MC., Iismaa SE., Xiao XH., Friedrich O., Wagner S., Nikolova-Krstevski V., Wu J., Yu ZY., Feneley M., Fatkin D., Allen DG., Graham RM.:
    Regulation of murine cardiac contractility by activation of α(1A)-adrenergic receptor-operated Ca(2+) entry.
    In: Cardiovascular Research 91 (2011), S. 310-9
    ISSN: 0008-6363
    DOI: 10.1093/cvr/cvr081
    URL: http://cardiovascres.oxfordjournals.org/content/cardiovascres/91/2/310.full.pdf
  • Sinner B., Friedrich O., Zausig Y., Bein T., Graf B.:
    Toxic effects of midazolam on differentiating neurons in vitro as a consequence of suppressed neuronal Ca 2+-oscillations
    In: Toxicology 290 (2011), S. 96-101
    ISSN: 0300-483X
    DOI: 10.1016/j.tox.2011.08.022
    URL: http://www.sciencedirect.com/science/article/pii/S0300483X1100326X
  • Sinner B., Friedrich O., Zink W., Zausig Y., Graf B.:
    The toxic effects of s(+)-ketamine on differentiating neurons in vitro as a consequence of suppressed neuronal Ca2+ oscillations.
    In: Anesthesia and analgesia 113 (2011), S. 1161-9
    ISSN: 1526-7598
    DOI: 10.1213/ANE.0b013e31822747df
    URL: http://journals.lww.com/anesthesia-analgesia/pages/articleviewer.aspx?year=2011&issue=11000&article=00033&type=abstract
  • Völkers M., Weidenhammer C., Herzog N., Qiu G., Spaich K., von Wegner F., Peppel K., Müller OJ., Schinkel S., Rabinowitz JE., Hippe HJ., Brinks H., Katus H., Koch WJ., Eckhart AD., Friedrich O., Most P.:
    The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.
    In: Circulation Research 108 (2011), S. 27-39
    ISSN: 1524-4571
    DOI: 10.1161/CIRCRESAHA.110.225201
    URL: http://circres.ahajournals.org/content/108/1/27

2010

  • Balansa W., Islam R., Fontaine F., Piggott A., Zhang H., Webb T., Gilbert D., Lynch J., Capon R.:
    Ircinialactams: subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae.
    In: Bioorganic & medicinal chemistry 18 (2010), S. 2912-9
    ISSN: 1464-3391
    DOI: 10.1016/j.bmc.2010.03.002
  • Chung S., Vanbellinghen J., Mullins J., Robinson A., Hantke J., Hammond C., Gilbert D., Freilinger M., Ryan M., Kruer M., Masri A., Gurses C., Ferrie C., Harvey K., Shiang R., Christodoulou J., Andermann F., Andermann E., Thomas R., Harvey R., Lynch J., Rees M.:
    Pathophysiological mechanisms of dominant and recessive GLRA1 mutations in hyperekplexia.
    In: The Journal of Neuroscience 30 (2010), S. 9612-20
    ISSN: 1529-2401
    DOI: 10.1523/JNEUROSCI.1763-10.2010
  • Edwards JN., Friedrich O., Cully TR., von Wegner F., Murphy RM., Launikonis BS.:
    Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle.
    In: American journal of physiology. Cell physiology 299 (2010), S. C42-50
    ISSN: 1522-1563
    DOI: 10.1152/ajpcell.00524.2009
    URL: http://ajpcell.physiology.org/content/299/1/C42
  • Edwards JN., Murphy RM., Cully TR., von Wegner F., Friedrich O., Launikonis BS.:
    Ultra-rapid activation and deactivation of store-operated Ca(2+) entry in skeletal muscle.
    In: Cell calcium 47 (2010), S. 458-67
    ISSN: 1532-1991
    DOI: 10.1016/j.ceca.2010.04.001
    URL: http://www.sciencedirect.com/science/article/pii/S0143416010000643
  • Friedrich O.:
    One arm is enough, two might actually be worse--when dystrophic muscle cells grow old.
    In: Experimental physiology 95 (2010), S. 607-8
    ISSN: 1469-445X
    DOI: 10.1113/expphysiol.2010.052621
    URL: http://onlinelibrary.wiley.com/doi/10.1113/expphysiol.2010.052621/abstract;jsessionid=F29D8110155C6F20FBEAE1A259AC4245.f01t03
  • Friedrich O.:
    Pressure, the nervous system and ion channels: Are humans too complicated?
    In: Undersea & Hyperbaric Medicine 37 (2010), S. 241-243
    ISSN: 1066-2936
    URL: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78149275225∨igin=inward
  • Friedrich O., Both M., Weber C., Schürmann S., Teichmann MDH., von Wegner F., Fink R., Vogel M., Chamberlain JS., Garbe CS.:
    Microarchitecture is severely compromised but motor protein function is preserved in dystrophic mdx skeletal muscle.
    In: Biophysical Journal 98 (2010), S. 606-16
    ISSN: 0006-3495
    DOI: 10.1016/j.bpj.2009.11.005
    URL: http://www.cell.com/biophysj/abstract/S0006-3495%2809%2901728-7
  • Friedrich O., Fink R., von Wegner F.:
    New factors contributing to dynamic calcium regulation in the skeletal muscle triad-a crowded place
    In: Biophysical Reviews 2 (2010), S. 29-38
    ISSN: 1867-2450
    DOI: 10.1007/s12551-009-0027-2
  • Friedrich O., Hund E., von Wegner F.:
    Enhanced muscle shortening and impaired Ca2+ channel function in an acute septic myopathy model.
    In: Journal of Neurology 257 (2010), S. 546-55
    ISSN: 0340-5354
    DOI: 10.1007/s00415-009-5362-5
    URL: http://link.springer.com/article/10.1007%2Fs00415-009-5362-5
  • Gebhardt F., Mitrovic A., Gilbert D., Vandenberg R., Lynch J., Dodd P.:
    Exon-skipping splice variants of excitatory amino acid transporter-2 (EAAT2) form heteromeric complexes with full-length EAAT2.
    In: Journal of Biological Chemistry 285 (2010), S. 31313-24
    ISSN: 0021-9258
    DOI: 10.1074/jbc.M110.153494
  • Schürmann S., von Wegner F., Fink R., Friedrich O., Vogel M.:
    Second harmonic generation microscopy probes different states of motor protein interaction in myofibrils
    In: Biophysical Journal 99 (2010), S. 1842-1851
    ISSN: 0006-3495
    DOI: 10.1016/j.bpj.2010.07.005
  • Völkers M., Salz M., Herzog N., Frank D., Dolatabadi N., Frey N., Gude N., Friedrich O., Koch WJ., Katus H., Sussmann MA., Most P.:
    Orai1 and Stim1 regulate normal and hypertrophic growth in cardiomyocytes.
    In: Journal of molecular and cellular cardiology 48 (2010), S. 1329-34
    ISSN: 1095-8584
    DOI: 10.1016/j.yjmcc.2010.01.020
    URL: http://www.jmmc-online.com/article/S0022-2828%2810%2900033-7/abstract

2009

  • Bartz F., Kern L., Erz D., Zhu M., Gilbert D., Meinhof T., Wirkner U., Erfle H., Muckenthaler M., Pepperkok R., Runz H.:
    Identification of cholesterol-regulating genes by targeted RNAi screening.
    In: Cell metabolism 10 (2009), S. 63-75
    ISSN: 1932-7420
    DOI: 10.1016/j.cmet.2009.05.009
  • Gilbert D., Esmaeili A., Lynch J.:
    Optimizing the expression of recombinant alphabetagamma GABAA receptors in HEK293 cells for high-throughput screening.
    In: Journal of Biomolecular Screening 14 (2009), S. 86-91
    ISSN: 1087-0571
    DOI: 10.1177/1087057108328017
  • Gilbert D., Islam R., Lynagh T., Lynch J., Webb T.:
    High Throughput Techniques for Discovering New Glycine Receptor Modulators and their Binding Sites.
    In: Frontiers in Molecular Neuroscience 2 (2009), S. 17
    ISSN: 1662-5099
    DOI: 10.3389/neuro.02.017.2009
  • Gilbert D., Meinhof T., Pepperkok R., Runz H.:
    DetecTiff: a novel image analysis routine for high-content screening microscopy.
    In: Journal of biomolecular screening 14 (2009), S. 944-55
    ISSN: 1552-454X
    DOI: 10.1177/1087057109339523
  • Gilbert D., Wilson J., Nink V., Lynch J., Osborne G.:
    Multiplexed labeling of viable cells for high-throughput analysis of glycine receptor function using flow cytometry.
    In: Cytometry. Part A : the journal of the International Society for Analytical Cytology 75 (2009), S. 440-9
    ISSN: 1552-4930
    DOI: 10.1002/cyto.a.20703
  • Launikonis BS., Stephenson DG., Friedrich O.:
    Rapid Ca2+ flux through the transverse tubular membrane, activated by individual action potentials in mammalian skeletal muscle.
    In: The Journal of Physiology 587 (2009), S. 2299-312
    ISSN: 0022-3751
    DOI: 10.1113/jphysiol.2009.168682
    URL: http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2009.168682/full
  • von Wegner F., Schürmann S., Fink R., Vogel M., Friedrich O.:
    Motor protein function in skeletal muscle-a multiple scale approach to contractility.
    In: IEEE transactions on medical imaging 28 (2009), S. 1632-42
    ISSN: 1558-254X
    DOI: 10.1109/TMI.2009.2026171
    URL: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=5153360

2008

  • Friedrich O.:
    Critical illness myopathy: Sepsis-mediated failure of the peripheral nervous system
    In: European Journal of Anaesthesiology 25 (2008), S. 73-82
    ISSN: 0265-0215
    DOI: 10.1017/S0265021507003262
  • Friedrich O., Weber C., von Wegner F., Chamberlain JS., Fink R.:
    Unloaded speed of shortening in voltage-clamped intact skeletal muscle fibers from wt, mdx, and transgenic minidystrophin mice using a novel high-speed acquisition system.
    In: Biophysical Journal 94 (2008), S. 4751-65
    ISSN: 0006-3495
    DOI: 10.1529/biophysj.107.126557
    URL: http://www.cell.com/biophysj/abstract/S0006-3495%2808%2970342-4
  • Friedrich O., von Wegner F., Chamberlain JS., Fink R., Rohrbach P.:
    L-type Ca2+ channel function is linked to dystrophin expression in mammalian muscle.
    In: PLoS ONE 3 (2008), S. e1762
    ISSN: 1932-6203
    DOI: 10.1371/journal.pone.0001762
    URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001762
  • Schnee S., von Wegner F., Schürmann S., Ludwig H., Fink R., Friedrich O.:
    Microdomain Ca2+ dynamics in mammalian muscle following prolonged high pressure treatments
    In: Journal of Physics : Conference Series 121 (2008), Art.Nr.: 112003
    ISSN: 1742-6588
    DOI: 10.1088/1742-6596/121/11/112003
  • Teichmann MDH., von Wegner F., Fink R., Chamberlain JS., Launikonis BS., Martinac B., Friedrich O.:
    Inhibitory control over Ca(2+) sparks via mechanosensitive channels is disrupted in dystrophin deficient muscle but restored by mini-dystrophin expression.
    In: PLoS ONE 3 (2008), S. e3644
    ISSN: 1932-6203
    DOI: 10.1371/journal.pone.0003644
    URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003644
  • von Wegner F., Koyama S., Miwa T., Friedrich O.:
    Resting membrane potentials recorded on-site in intact skeletal muscles from deep sea fish (Sigmops gracile) salvaged from depths up to 1.000 m.
    In: Marine Biotechnology 10 (2008), S. 478-86
    ISSN: 1436-2228
    DOI: 10.1007/s10126-008-9085-x
    URL: http://link.springer.com/article/10.1007/s10126-008-9085-x
  • von Wegner F., Ober T., Weber C., Schürmann S., Winter R., Friedrich O., Fink R., Vogel M.:
    Velocity distributions of single F-actin trajectories from a fluorescence image series using trajectory reconstruction and optical flow mapping.
    In: Journal of Biomedical Optics 13 (2008), S. 054018
    ISSN: 1083-3668
    DOI: 10.1117/1.2982525

2007

  • Friedrich O., von Wegner F., Wink M., Fink R.:
    NA+- and K+-channels as molecular targets of the alkaloid ajmaline in skeletal muscle fibres.
    In: British Journal of Pharmacology 151 (2007), S. 82-93
    ISSN: 0007-1188
    DOI: 10.1038/sj.bjp.0707194
    URL: http://onlinelibrary.wiley.com/doi/10.1038/sj.bjp.0707194/abstract;jsessionid=46E49C62B38C2F13EFC6BA6486CB62A6.f04t01
  • Gilbert D., Franjic-Würtz C., Funk K., Gensch T., Frings S., Möhrlen F.:
    Differential maturation of chloride homeostasis in primary afferent neurons of the somatosensory system.
    In: International Journal of Developmental Neuroscience 25 (2007), S. 479-89
    ISSN: 0736-5748
    DOI: 10.1016/j.ijdevneu.2007.08.001
  • Gilbert D., Funk K., Dekowski B., Lechler R., Keller S., Möhrlen F., Frings S., Hagen V.:
    Caged capsaicins: New tools for the examination of TRPV1 channels in somatosensory neurons.
    In: ChemBioChem 8 (2007), S. 89-97
    ISSN: 1439-4227
    DOI: 10.1002/cbic.200600437
  • Völkers M., Loughrey CM., MacQuaide N., Remppis BA., DeGeorge BR., von Wegner F., Friedrich O., Fink R., Koch WJ., Smith GL., Most P.:
    S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes.
    In: Cell Calcium 41 (2007), S. 135-43
    ISSN: 0143-4160
    DOI: 10.1016/j.ceca.2006.06.001
    URL: http://www.sciencedirect.com/science/article/pii/S0143416006001138
  • von Wegner F., Both M., Fink R., Friedrich O.:
    Fast XYT imaging of elementary calcium release events in muscle with multifocal multiphoton microscopy and wavelet denoising and detection.
    In: IEEE Transactions on Medical Imaging 26 (2007), S. 925-34
    ISSN: 0278-0062
    DOI: 10.1109/TMI.2007.895471
    URL: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=4265757

2006

  • Friedrich O.:
    Critical illness myopathy: What is happening?
    In: Current Opinion in Clinical Nutrition and Metabolic Care 9 (2006), S. 403-409
    ISSN: 1363-1950
    DOI: 10.1097/01.mco.0000232900.59168.a0
  • Friedrich O., Hund E.:
    Critical illness myopathy in intensive care patients: Pathogenetic concepts and clinical management
    In: Anaesthesist 55 (2006), S. 1271-1280
    ISSN: 0003-2417
    DOI: 10.1007/s00101-006-1100-x
  • Friedrich O., Kress K., Hartmann M., Frey B., Sommer K., Ludwig H., Fink R.:
    Prolonged high-pressure treatments in mammalian skeletal muscle result in loss of functional sodium channels and altered calcium channel kinetics.
    In: Cell Biochemistry and Biophysics 45 (2006), S. 71-83
    ISSN: 1085-9195
    DOI: 10.1385/CBB:45:1:71
  • Friedrich O., von Wegner F., Hartmann M., Frey B., Sommer K., Ludwig H., Fink R.:
    'In situ' high pressure confocal Ca2+-fluorescence microscopy in skeletal muscle: A new method to study pressure limits in mammalian cells
    In: Undersea & Hyperbaric Medicine 33 (2006), S. 181-95
    ISSN: 1066-2936
    URL: https://www.scopus.com/record/display.uri?eid=2-s2.0-33746618017∨igin=inward
  • Rohrbach P., Sanchez CP., Hayton K., Friedrich O., Patel J., Singh Sidhu AB., Ferdig MT., Fidock DA., Lanzer M.:
    Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum.
    In: EMBO Journal 25 (2006), S. 3000-11
    ISSN: 0261-4189
    DOI: 10.1038/sj.emboj.7601203
  • Sinner B., Friedrich O., Zink W., Fink R., Graf B.:
    GABAmimetic intravenous anaesthetics inhibit spontaneous Ca 2+-oscillations in cultured hippocampal neurons
    In: Acta Anaesthesiologica Scandinavica 50 (2006), S. 742-748
    ISSN: 0001-5172
    DOI: 10.1111/j.1399-6576.2006.01031.x
  • von Wegner F., Both M., Fink R., Friedrich O.:
    Elementary Ca2+ release events in mammalian skeletal muscle: effects of the anaesthetic drug thiopental.
    In: Journal of Muscle Research and Cell Motility 27 (2006), S. 315-26
    ISSN: 0142-4319
    DOI: 10.1007/s10974-006-9092-3

2005

  • Friedrich O., Fink R., Hund E.:
    Understanding critical illness myopathy: approaching the pathomechanism.
    In: Journal of Nutrition 135 (2005), S. 1813S-1817S
    ISSN: 0022-3166
    DOI: 10.1093/jn/135.7.1813S
  • Kruger W., Gilbert D., Hawthorne R., Hryciw D., Frings S., Poronnik P., Lynch J.:
    A yellow fluorescent protein-based assay for high-throughput screening of glycine and GABAA receptor chloride channels.
    In: Neuroscience Letters 380 (2005), S. 340-5
    ISSN: 0304-3940
    DOI: 10.1016/j.neulet.2005.01.065
  • Nolte F., Friedrich O., ROjewski M., Fink R., Schrezenmeier H., Körper S.:
    Erratum: Depolarisation of the plasma membrane in the arsenic trioxide (As2O3)- and anti-CD95-induced apoptosis in myeloid cells (FEBS 29005) (FEBS Letters (2004) 578 (85-89) DOI 10.1016/j.febslet.2004.10.075)
    In: Febs Letters 579 (2005)
    ISSN: 0014-5793
    DOI: 10.1016/j.febslet.2005.05.037
  • Rohrbach P., Friedrich O., Hentschel J., Plattner H., Fink R., Lanzer M.:
    Quantitative calcium measurements in subcellular compartments of Plasmodium falciparum-infected erythrocytes
    In: Journal of Biological Chemistry 280 (2005), S. 27960-27969
    ISSN: 0021-9258
    DOI: 10.1074/jbc.M500777200
  • Sinner B., Friedrich O., Zink W., Martin EO., Fink R., Graf BM.:
    Ketamine stereoselectively inhibits spontaneous Ca2+-oscillations in cultured hippocampal neurons.
    In: Anesthesia and Analgesia 100 (2005), S. 1660-6
    ISSN: 0003-2999
    DOI: 10.1213/01.ANE.0000150946.18875.48

2004

  • Both M., Vogel M., Friedrich O., von Wegner F., Künsting T., Fink R., Uttenweiler D.:
    Second harmonic imaging of intrinsic signals in muscle fibers in situ.
    In: Journal of Biomedical Optics 9 (2004), S. 882-92
    ISSN: 1083-3668
    DOI: 10.1117/1.1783354
  • Friedrich O., Both M., Gillis JM., Chamberlain JS., Fink R.:
    Mini-dystrophin restores L-type calcium currents in skeletal muscle of transgenic mdx mice.
    In: The Journal of Physiology 555 (2004), S. 251-65
    ISSN: 0022-3751
    DOI: 10.1113/jphysiol.2003.054213
  • Friedrich O., Hund E., Weber C., Hacke W., Fink R.:
    Critical illness myopathy serum fractions affect membrane excitability and intracellular calcium release in mammalian skeletal muscle.
    In: Journal of Neurology 251 (2004), S. 53-65
    ISSN: 0340-5354
    DOI: 10.1007/s00415-004-0272-z
  • Nessler S., Friedrich O., Bakouh N., Fink R., Sanchez CP., Planelles G., Lanzer M.:
    Evidence for activation of endogenous transporters in Xenopus laevis oocytes expressing the Plasmodium falciparum chloroquine resistance transporter, PfCRT.
    In: Journal of Biological Chemistry 279 (2004), S. 39438-46
    ISSN: 0021-9258
    DOI: 10.1074/jbc.M404671200
  • Nolte F., Friedrich O., ROjewski M., Fink R., Schrezenmeier H., Körper S.:
    Depolarisation of the plasma membrane in the arsenic trioxide (As2O3)-and anti-CD95-induced apoptosis in myeloid cells.
    In: Febs Letters 578 (2004), S. 85-9
    ISSN: 0014-5793
    DOI: 10.1016/j.febslet.2004.10.075

2002

  • Friedrich O, Kress KR, Ludwig H, Fink RH:
    Membrane ion conductances of mammalian skeletal muscle in the post-decompression state after high-pressure treatment.
    In: Journal of Membrane Biology 188 (2002), S. 11-22
    ISSN: 0022-2631
    DOI: 10.1007/s00232-001-0168-0

2001

  • Friedrich O., Ehmer T., Uttenweiler D., Vogel M., Barry PH., Fink R.:
    Numerical analysis of Ca2+ depletion in the transverse tubular system of mammalian muscle.
    In: Biophysical Journal 80 (2001), S. 2046-55
    ISSN: 0006-3495
    DOI: 10.1016/S0006-3495(01)76178-4
  • Friedrich O., Kress K., Ludwig H., Fink R.:
    Reversibility of high pressure effects on the contractility of skeletal muscle.
    In: Journal of Muscle Research and Cell Motility 22 (2001), S. 379-89
    ISSN: 0142-4319

1999

  • Friedrich O., Ehmer T., Fink R.:
    Calcium currents during contraction and shortening in enzymatically isolated murine skeletal muscle fibres.
    In: The Journal of Physiology 517 ( Pt 3) (1999), S. 757-70
    ISSN: 0022-3751
    DOI: 10.1111/j.1469-7793.1999.0757s.x
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