Graduation
Application
We appreciate your interest in our Institute. Even if there are no available graduation topics explicitly listed below, we welcome your unsolicited application.
Doctoral Degree (Dr.Ing. - Dr.rer.biol.hum.)
Master's Thesis (M.Sc.)
Muscle Regeneration
Centralized nuclei appear to remain after muscle regenerated from damage. They line up in the centre of the muscle fibre, potentially impeding the linear alignment of force generating units. The effect of these nuclei on muscle performance and the sarcomere lattice array (directed force generation) is vastly unknown. To change this, you will carry out functional recordings with our MyoRobot and quantitative imaging using SHG microscopy.
For further information please contact Dr. Michael Haug
Master’s Thesis – Muscle Regeneration
Brain Archive
Develop a brain bioreactor for the cryo-conservation of porcine brain tissue.
More details can be found in the PDF below.
For further information please contact Paul Ritter or Dr. Michael Haug
Master’s Thesis – Brain Archive
Perfusions-Simulation
Simulation of dynamic perfusion of 3D-printed scaffolds with minifluidic testing.
More details can be found in the PDF below.
For further information please contact Dr. Martin Vielreicher
Master’s Thesis – Perfusions-Simulation
Impact of ulcerative colitis on skeletal muscle performance
Patients suffering from inflammatory bowel disease (IBD) describe muscle weakness and limited motility, particularly in their extremities. Just like the eventual cause for the disease itself, the rationale behind muscle weakness in IBD remains speculative and a potential cure or amelioration remains to be found. Therefore, we conduct a comparative pilot study governing the entity of most common active and passive biomechanics recordings to characterize performance losses in an IBD mouse model.
More details can be found in the PDF below.
For further information please contact Dr. Michael Haug or Mena Michael.
Master’s Thesis – Ulcerative Colitis
MyoRobot 3.0 - Stretch-correction & auto-focus LWD Optics System
Online structure-function recordings, e.g. the sarcomere length distribution during active contraction or (in)homogeneity during passive hysteresis stretches, require three essential properties not governed by the current setup. This limits the ease of application for the user and represents a thorn in the otherwise fully automated system for pre-clinical muscle diagnostics. Therefore, we plan on implementing a high resolution long-working-distance (LWD) optical platform, featuring stretch-correction and auto-focus functionality.
More details can be found in the PDF below.
For further information please contact Dr. Michael Haug or Mena Michael.
Master’s Thesis – Auto-focus LWD Optics System
Bachelor's Thesis (B.Sc.)
Perfusions-Simulation
Simulation of dynamic perfusion of 3D-printed scaffolds with minifluidic testing.
More details can be found in the PDF below.
For further information please contact Dr. Martin Vielreicher
Bachelor’s Thesis – Perfusions-Simulation
